Autoinflammatory diseases unit
French National referral centre
Biology-Pathology research pole - University Hospital of Montpellier


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Auto-inflammatory and chronic osteoarticular disorders represent an enormous socio-economic burden for our society. Systemic auto-inflammatory disorders (SAID) are defined as illnesses caused by primary dysfunction of the innate immune system. These diseases encompass a wide spectrum of disorders characterised by recurrent attacks of fever, abdominal pain, arthritis and cutaneous signs, which sometimes overlap obscuring the diagnosis. Rheumatoid arthritis (RA) and JIA (juvenile idiopathic arthritis) are systemic and chronic inflammatory diseases, which manifest in multiple joints. Although very different in their manifestations, most of these diseases are considered to result upon a failure of the immune system’s auto-regulatory mechanisms. The aetiology of disease remains a matter of debate in many instances.


Réalisé par Florian Milhavet   |   Mentions légales   |   Contact & Plan d'accès